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TA-65 Research

The Telomere Science Library is a collection of news articles, medical journal abstracts (and links) and information about telomeres and telomerase.

Beyond average: potential for measurement of short telomeres. Aging (Albany NY). 2012 Jun 8. Vera E, Blasco MA.

CNIO scientists successfully test the first gene therapy against aging-associated decline 14-May-2012 Centro Nacional de Investigaciones Oncologicas (CNIO)

Shorter telomere length is associated with increased ovarian cancer risk in both familial and sporadic cases. J Med Genet. 2012 May;49(5):341-4. Epub 2012 Apr 6. Martinez-Delgado B et al

The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder. J Affect Disord. 2011 Dec;135(1-3):43-50. Epub 2011 Aug 30. Elvsåshagen T et al

The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence. Aging Cell. 2011 Aug;10(4):604-21. doi: 10.1111/j.1474-9726.2011.00700. Blasco MA et al

Biologic function and clinical potential of telomerase and associated proteins in cardiovascular tissue repair and regeneration. Eur Heart J. 2011 May;32(10):1190-6. Madonna R et all A natural product telomerase activator as part of a health maintenance program.Rejuvenation Res. 2011 Feb;14(1):45-56. Harley CB et al

María Blasco: Keeping a cap on cancer and aging Interview by Caitlin Sedwick. J Cell Biol. 2011 Feb 7;192(3):370-1 Blasco M.

Telomeres in cancer and aging. Philos Trans R Soc Lond B Biol Sci. 2011 Jan 12;366(1561):76-84. Donate LE, Blasco MA.

Aging by telomere loss can be reversed. Cell Stem Cell. 2011 Jan 7;8(1):3-4. Bernardes de Jesus B, Blasco MA.

The role of telomeres and telomerase in stem cell aging. FEBS Lett. 2010 Sep 10;584(17): 3826-30. Flores I, Blasco MA.

Telomere shortening and aging of the immune system. J Physiol Pharmacol. 2008 Dec;59 Suppl 9:169-86. Kaszubowska L.

Telomerase deficiency promotes oxidative stress by reducing catalase activity. Free Radic Biol Med. 2008 Nov 1;45(9):1243-51. Epub 2008 Jul 30. Pérez-Rivero G et al

Telomeres and aging  Physiol Rev. 2008 Apr;88(2):557-79. Aubert G, Lansdorp PM.

Telomerase induction in T cells: a cure for aging and disease? Exp Gerontol. 2007 May;42(5):416-20. Epub 2006 Dec 19.

TA-65® has been in use since 2005 with not one reported adverse event.